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December 2022: Wave Life Sciences announced a positive update from the initial cohort of the Phase 1b/2a study of WVE-N531 in three boys with Duchenne muscular dystrophy (DMD) amenable to exon 53 skipping. They are encouraged by these early results and what they may mean for WVE-N531’s potential to restore meaningful levels of dystrophin with continued dosing.
Read the below press release and letter to the community: